The Collaborative Neuroimaging Environment for Connectomics at the University of Illinois Chicago (CoNECt@UIC) is an interdisciplinary team of researchers and clinicians devoted to improving our understanding of brain connectivity using novel techniques from neuroimaging and computational neuroscience. We have applied these innovative brain mapping methods to elucidate mechanisms associated with a wide variety of clinical conditions such as diabetes and depression, bipolar disorder, Fragile X, geriatric depression, and body dysmorphic disorder.